Docking Studies on the Effects of Some Bioactive Compounds from Pistacia atlantica Desf. against Main Protease SARS-CoV2

Novel coronavirus which was named later as SARS-CoV2 appeared in Wuhan, China, the end of December 2019. Actually, no precise drugs are existed and research concerning treatment is deficient. main protease (Mpro) crystallized by Liu et al. (2020) represented a crucial drug target. The present work aimed to evaluate some bioactive compounds from Pistacia atlantica possible Mpro inhibitors, based on molecular docking approach. Molecular carried out using AutoDock Vina software. results indicated that Beta-Eudesmol, Elemol, Verbenol, Pinocarvone, Myrtenal, Myrtenol Trans-Carveol have potential inhibitor activity Mpro. Nevertheless, further investigations required develop optimize process combat SARS-CoV2.